Hotels in San Diego City Center, CA

Find the Top Central hotels in San Diego – 70+ Quality Options from Leading Providers

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MapView on map1700 yd from City Center400 yd from House of Blues San Diego
From   US$ 163 /nightSelect
  • Unique industrial design with modern amenities
  • Vibrant nightlife atmosphere in Gaslamp Quarter
  • Dual shower heads for an exceptional experience
MapView on map1700 yd from City Center400 yd from House of Blues San Diego
From   US$ 143 /nightSelect
  • Rooftop pool with stunning skyline views
  • On-site Bronze Bird restaurant for dining
  • Pet-friendly with special amenities for dogs
  • Grant Grill
  • Event Spaces
  • Valet Parking
1500 yd from City Center200 yd from House of Blues San Diego
From   US$ 275 /nightSelect
  • Historic venue with Prohibition-era event spaces
  • AAA Four Diamond dining at Grant Grill
  • Convenient access to Gaslamp Quarter attractions
  • Outdoor Pool
  • Gym Facilities
  • On-site Dining
1800 yd from City Center500 yd from Santa Fe Depot
From   US$ 124 /nightSelect
  • Stunning bay views from guest rooms
  • Complimentary airport shuttle service
  • Pet-friendly accommodations available
  • Rooftop Bar
  • Health Center
  • Floor-to-Ceiling Windows
1.0 mi from City Center300 yd from Santa Fe Depot
From   US$ 260 /nightSelect
  • Elegant meeting and event space
  • Italian-inspired speakeasy dining
  • Coastal-inspired culinary experiences
  • Indoor Pool
  • Fitness Center
  • On-site Dining
1100 yd from City Center400 yd from House of Blues San Diego
From   US$ 67 /nightSelect
  • Kids club with fun activities
  • Live music at the lobby bar
  • Complimentary daily treats offered
  • Fitness Centre
  • The Guild Bar
  • Outdoor Dining
1700 yd from City Center200 yd from Santa Fe Depot
From   US$ 49 /nightSelect
  • Historic building with modern luxury
  • Prime downtown location near attractions
  • Elegant venues for memorable events
  • Rooftop Pool
  • On-site Dining
  • Fitness Center
From   US$ 176 /nightSelect
  • Stunning rooftop pool with city views
  • Vibrant bar with live music events
  • Coastal cuisine with local flavors
  • Rooftop Pool
  • Business Center
  • Spa Amenities
1700 yd from City Center300 yd from Santa Fe Depot
From   US$ 197 /nightSelect
  • Breathtaking bay view rooms
  • Outstanding in-house dining experiences
  • Complimentary bicycle rentals available
  • Rooftop Pool
  • Pet-Friendly
  • Wine Hour
From   US$ 212 /nightSelect
  • Rooftop pool with skyline views
  • Pet-friendly stays with no extra charges
  • Daily wine hour for guest enjoyment
  • Rooftop Bar
  • Executive Lounge
  • Fitness Center
1500 yd from City Center400 yd from Santa Fe Depot
From   US$ 126 /nightSelect
  • Rooftop bar with fire pit
  • Executive lounge with outdoor seating
  • Complimentary early check-in
  • Rooftop Bar
  • Saltwater Pool
  • Fitness Center
1300 yd from City Center500 yd from Santa Fe Depot
From   US$ 253 /nightSelect
  • Rooftop bar with stunning bay views
  • Saltwater pool on the rooftop
  • Unique fitness center partnership
  • Rooftop Bar
  • Fitness Center
  • Dining Options
1.2 mi from City Center400 yd from Petco Park
From   US$ 189 /nightSelect
  • Rooftop bar with stunning city views
  • Pet-friendly with complimentary dog amenities
  • Award-winning, eco-friendly hotel design
  • Outdoor Pool
  • Fitness Center
  • Business Center
2.5 mi from City Center1200 yd from Fashion Valley Mall
From   US$ 139 /nightSelect
  • Mountain view rooms enhance guest experience
  • Polanco Kitchen & Bar with Latin cuisine
  • Spacious conference facilities for events
9.2
Perfect1 review
  • Yoga Studio
  • Bike Rentals
  • Spa Services
1600 yd from City Center500 yd from House of Blues San Diego
From   US$ 140 /nightSelect
  • Historic boutique hotel with unique character
  • Free yoga classes enhance wellness experience
  • Complimentary dog treats for pet owners
  • Rooftop Pool
  • Private Dining
  • Fitness Center
1400 yd from City Center100 yd from House of Blues San Diego
From   US$ 249 /nightSelect
  • Rooftop pool with stunning city views
  • Complimentary wine and cheese hour
  • Dog-friendly with special amenities
  • Rooftop Pool
  • Wellness Club
  • Fine Dining
1500 yd from City Center300 yd from House of Blues San Diego
From   US$ 179 /nightSelect
  • Palace of Versailles inspired elegance
  • Rooftop pool with city views
  • Four-story fitness and wellness club
  • M Club Lounge
  • Outdoor Pool
  • Fitness Center
3.5 mi from City Center
From   US$ 176 /nightSelect
  • Exclusive M Club Lounge access
  • Breathtaking pool with cabanas
  • Close to Snapdragon Stadium events
  • Outdoor Pool
  • Fitness Centre
  • On-site Restaurant
1400 yd from City Center1200 yd from Santa Fe Depot
From   US$ 197 /nightSelect
  • Fully equipped kitchens in every suite
  • Year-round outdoor swimming pool
  • On-site fitness centre available
  • Charming Courtyard
  • On-site Restaurant
  • Fitness Center
1.2 mi from City Center600 yd from Petco Park
From   US$ 148 /nightSelect
  • Victorian-style rooms with gas fireplaces
  • Live jazz entertainment at Salt & Whiskey
  • Charming courtyard with historical allure
  • Cru Bistro
  • Outdoor Pool
  • Fitness Center
2.6 mi from City Center1800 yd from Fashion Valley Mall
From   US$ 135 /nightSelect
  • Pure Rooms for wellness-focused travelers
  • Innovative California cuisine at Cru Bistro
  • Extensive event space for meetings
  • Rooftop Pool
  • Fitness Center
  • On-site Restaurant
1400 yd from City Center1200 yd from Santa Fe Depot
From   US$ 180 /nightSelect
  • Rooftop pool with stunning views
  • On-site restaurant offers daily meals
  • 24-hour fitness center available
  • Rooftop Pool
  • Fitness Center
  • On-site Bar
1.1 mi from City Center300 yd from Santa Fe Depot
From   US$ 263 /nightSelect
  • Rooftop pool with stunning bay views
  • Complimentary breakfast with diverse offerings
  • Accessible public transport options nearby
  • Fitness Center
  • Bar Moxy
  • Meeting Spaces
1700 yd from City Center400 yd from House of Blues San Diego
From   US$ 219 /nightSelect
  • Unique speakeasy with curated cocktails
  • Room designs maximizing every inch of space
  • Social hub with craft drinks and games
  • Business Center
  • Daily Maid Service
  • Complimentary Breakfast
1.0 mi from City Center500 yd from House of Blues San Diego
From   US$ 91 /nightSelect
  • Secret courtyard for quiet relaxation
  • Complimentary large breakfast variety
  • Business center with new computers
9.4
Perfect1 review
  • Rooftop Deck
  • French Diner
  • Vintage Elevators
1700 yd from City Center400 yd from House of Blues San Diego
From   US$ 92 /nightSelect
  • Rooftop deck with stunning city views
  • 24-hour dining at St. James Diner
  • Historic elevators with vintage charm
  • Vault Meeting Room
  • On-site Bar
  • Fitness Center
1400 yd from City Center100 yd from House of Blues San Diego
From   US$ 97 /nightSelect
  • Historic bank vault meeting room
  • Authentic bar with local beers
  • Spacious suites with historical charm
  • Rooftop Pool
  • Fitness Center
  • Breakfast Buffet
1500 yd from City Center600 yd from Santa Fe Depot
From   US$ 149 /nightSelect
  • Rooftop pool with stunning bay views
  • Adjacent to waterfront park attractions
  • Interactive lobby with daily riddle
800 yd from City Center900 yd from House of Blues San Diego
From   US$ 139 /nightSelect
Offering the outdoor swimming pool, the 3-star Four Points By Sheraton San Diego Downtown Little Italy San Diego boasts a location a 6-minute walk from Little Italy.
  • Event Space
  • Accessible Rooms
  • Parking Options
1100 yd from City Center800 yd from Santa Fe Depot
From   US$ 115 /nightSelect
  • Pet-friendly accommodations with no hidden fees
  • In the heart of vibrant Little Italy
  • Personalized service from friendly staff
  • Outdoor Pool
  • Fitness Center
  • Business Center
3.3 mi from City Center
From   US$ 119 /nightSelect
  • Centrally located near major attractions
  • Outdoor heated pool with fire pit area
  • Accessible amenities for all guests
  • Rooftop Lounge
  • Kitchenette
  • Fitness Centre
1400 yd from City Center1000 yd from San Diego Zoo
From   US$ 160 /nightSelect
  • Rooftop lounge with stunning city views
  • Kitchenette facilities for family meals
  • Historic architecture reflecting local charm
  • King Suite
  • Outdoor Pool
  • Fitness Center
2.9 mi from City Center800 yd from Fashion Valley Mall
From   US$ 110 /nightSelect
  • Luxury King Presidential Suite with views
  • Outdoor pool with scenic dining options
  • Pet-friendly accommodations for travelers
  • Fitness Center
  • Business Center
  • Meeting Rooms
1500 yd from City Center400 yd from House of Blues San Diego
From   US$ 126 /nightSelect
  • Steps from Gaslamp Quarter nightlife
  • 1960s-inspired boutique hotel style
  • No resort fee for guests
  • Outdoor Pool
  • Business Center
  • Free Breakfast
900 yd from City Center500 yd from House of Blues San Diego
From   US$ 119 /nightSelect
  • Freshly made breakfast with diverse options
  • Complimentary shuttle service to attractions
  • Heated outdoor swimming pool available
  • Rooftop Terrace
  • Wine Parlor
  • Junior Suites
1600 yd from City Center300 yd from House of Blues San Diego
From   US$ 125 /nightSelect
  • Historic architecture with vintage charm
  • Rooftop terrace with city views
  • Wine parlor with unique ambiance
  • Heated pool
  • Hot tub
  • Fitness center
1400 yd from City Center500 yd from Santa Fe Depot
From   US$ 138 /nightSelect
  • Views of the historic Star of India
  • Heated outdoor pool and hot tub
  • Complimentary grab-and-go breakfast daily
  • Rooftop deck
  • Fitness center
  • Concierge service
1200 yd from City Center700 yd from House of Blues San Diego
From   US$ 167 /nightSelect
  • Rooftop deck with BBQ grills
  • Historic building with modern amenities
  • Pet-friendly accommodations available
  • Pineapple bikes
  • Water bar
  • Pet-friendly
1.2 mi from City Center500 yd from Petco Park
From   US$ 179 /nightSelect
  • Unique 'Naked Experience' bedding concept
  • Complimentary afternoon pineapple-themed snacks
  • Charming pineapple-themed decor throughout
  • Rooftop Lounge
  • Business Center
  • Pet-Friendly
1.0 mi from City Center300 yd from Santa Fe Depot
From   US$ 433 /nightSelect
  • Rooftop lounge with stunning bay views
  • Spacious suites with full kitchens
  • 24-hour fitness center and outdoor pool
  • Outdoor pool
  • On-site restaurant
  • Pet-friendly rooms
From   US$ 182 /nightSelect
  • Stunning views from higher floors
  • On-site restaurant with Californian cuisine
  • Complimentary cookies at check-in
  • Fitness Center
  • On-site Bar
  • Patio Area
900 yd from City Center600 yd from House of Blues San Diego
From   US$ 285 /nightSelect
  • Spacious suites with kitchenette
  • Robot service delivers to rooms
  • Complimentary breakfast for families
  • Game Room
  • Community Kitchen
  • Artistic Decor
1.1 mi from City Center600 yd from Petco Park
From   US$ 41 /nightSelect
  • Prime location in vibrant Gaslamp Quarter
  • Community kitchen encourages social interaction
  • Yoga and art events foster community spirit
  • On-site Laundry
  • Lockbox Check-In
  • Shared Kitchen
500 yd from City Center1000 yd from House of Blues San Diego
From   US$ 92 /nightSelect
  • Proximity to Balboa Park attractions
  • Artsy boutique atmosphere with local charm
  • Clean shared bathrooms for budget travelers
  • Outdoor Pool
  • Fitness Center
  • Snack Store
1400 yd from City Center900 yd from Santa Fe Depot
From   US$ 149 /nightSelect
  • Evening reception with wine and snacks
  • Spacious suites with full kitchens
  • Heated outdoor pool and fire pit
  • Rooftop Bar
  • Valet Parking
  • Heated Pool
1800 yd from City Center400 yd from House of Blues San Diego
From   US$ 182 /nightSelect
  • Breathtaking rooftop bar views
  • Convenient valet parking service
  • Proximity to San Diego Zoo
  • Rooftop Bar
  • Business Center
  • Fitness Center
1.2 mi from City Center400 yd from Petco Park
From   US$ 201 /nightSelect
  • Rooftop bar with stunning skyline views
  • Proximity to vibrant Gaslamp nightlife
  • Complimentary whiskey shot at check-in
  • Charming courtyard
  • Italian café
  • On-site dining
1200 yd from City Center900 yd from Santa Fe Depot
From   US$ 108 /nightSelect
  • Charming courtyard for relaxation
  • Authentic Italian dining options nearby
  • Free pastries and coffee voucher
  • Common Kitchen
  • Social Lounge
  • Private Lockers
1000 yd from City Center800 yd from Santa Fe Depot
From   US$ 45 /nightSelect
  • Social atmosphere for world travelers
  • Daily activities to connect with guests
  • Complimentary pancake bar breakfast
  • Full kitchens
  • Self-service laundry
  • Coded entry
1.1 mi from City Center600 yd from Petco Park
From   US$ 132 /nightSelect
  • Spacious mini-apartment style rooms
  • Digital check-in with code access
  • Proximity to vibrant nightlife scene
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