Hotels in Saint Louis City Centre, MO

Find the Top Central hotels in Saint Louis – 30+ Quality Options from Leading Providers

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MapView on map700 m from City Centre400 m from City Museum
From   US$ 112 /nightSelect
  • Complimentary hot breakfast daily
  • In-room kitchen facilities available
  • Pet-friendly accommodations offered
MapView on map1.8 km from City Centre400 m from The Dome at America's Center
From   US$ 319 /nightSelect
  • Arch-view rooftop pool with private cabanas
  • Gordon Ramsay dining with panoramic city views
  • Couples-only late-night spa experiences available
  • Fitness Center
  • Dining Options
  • Valet Parking
1.3 km from City Centre200 m from Gateway Arch
From   US$ 99 /nightSelect
  • Stunning views of the Gateway Arch
  • Built-in Chromecast for streaming content
  • Access to pet-friendly services
  • On-site Bar
  • Pet-Friendly
  • Fitness Center
From   US$ 109 /nightSelect
  • Historic bank building with unique features
  • Dining at award-winning Pennydrop Kitchen
  • Convenient access to downtown attractions
  • Indoor Pool
  • Kickback Hour
  • Pet Policy
1000 m from City Centre600 m from Union Station
From   US$ 100 /nightSelect
  • Kickback evening snacks and drinks
  • Pet-friendly environment
  • Year-round indoor pool
  • Fitness Center
  • Grab & Go Breakfast
  • Pet-Friendly
5.3 km from City Centre1.8 km from Saint Louis Science Center
From   US$ 142 /nightSelect
  • Complimentary fruit-infused hydration station
  • Historical charm of first St. Louis motel
  • Proximity to Washington University hospital
  • Art Museum
  • Wellness Center
  • Game Room
600 m from City Centre300 m from City Museum
From   US$ 287 /nightSelect
  • Unique art museum with interactive exhibits
  • Extensive wellness facilities including sauna
  • Sophisticated restaurant with exceptional dining
  • Grand Hall
  • Outdoor pool
  • Fitness center
600 m from City Centre200 m from Union Station
From   US$ 150 /nightSelect
  • Historic Grand Hall with stunning 3D light show
  • Multiple dining venues with diverse cuisine
  • Pet-friendly accommodations for your furry friends
  • Outdoor Pool
  • On-site Cinema
  • Fitness Center
From   US$ 280 /nightSelect
  • Historic architecture with Art Deco design
  • Mediterranean-style seasonal outdoor pool
  • On-site cinema with five screens
  • Connecting Rooms
  • Fitness Center
  • Business Center
5.2 km from City Centre1.3 km from Saint Louis Science Center
From   US$ 128 /nightSelect
  • Skybridge access to hospital facilities
  • Discounted rates for patient families
  • On-site dining at Applebee's
Bed & Breakfast
  • Outdoor pool
  • Sun terrace
  • Garden views
From   US$ 190 /nightSelect
  • Seasonal outdoor swimming pool
  • Pet-friendly accommodations available
  • Close to Forest Park attractions
  • Concierge Lounge
  • Fitness Center
  • Zenia Bar
1.1 km from City Centre300 m from America's Center
From   US$ 109 /nightSelect
  • Concierge lounge with complimentary meals
  • Modern decor and design throughout hotel
  • On-site Peloton bikes in fitness center
  • Rooftop Pool
  • Full-Service Spa
  • State-of-the-Art Fitness
1.0 km from City Centre500 m from America's Center
From   US$ 499 /nightSelect
  • Rooftop heated pool with city views
  • Artisanal cocktails at rooftop bar
  • Historical building with unique decor
  • Fitness Center
  • Meeting Space
  • Switch List
1.2 km from City Centre400 m from Gateway Arch
From   US$ 329 /nightSelect
  • Historic boutique decor with local touches
  • Pet-friendly accommodations for travelers
  • Onsite dining showcasing local flavors
  • Rooftop Pool
  • Ultima Cucina
  • Ballroom Spaces
From   US$ 345 /nightSelect
  • Historic shoe factory architecture
  • Rooftop pool with city views
  • Boutique dining at Ultima Cucina
  • Indoor Pool
  • Hair Salon
  • Fitness Center
1.4 km from City Centre300 m from America's Center
From   US$ 104 /nightSelect
  • Platinum Club of America since 2000
  • Full-service hair and nail salon
  • Elegant Missouri Ballroom for events
  • Indoor Pool
  • Kickback Dining
  • Pet-Friendly
1.2 km from City Centre200 m from Gateway Arch
From   US$ 110 /nightSelect
  • Complimentary evening Kickback with food
  • Indoor heated pool with lounge area
  • Views of the Gateway Arch available
  • Rooftop Bar
  • Art Galleries
  • Playroom
From   US$ 149 /nightSelect
  • Unique color-themed rooms inspire creativity
  • Rooftop bar with panoramic skyline views
  • Art installations throughout the hotel
  • Indoor Pool
  • Event Space
  • Hot Tub
1.4 km from City Centre200 m from America's Center
From   US$ 126 /nightSelect
  • Complimentary evening snacks and drinks
  • Convenient indoor pool and hot tub
  • Flexible event space for gatherings
  • Indoor Pool
  • EV Charging
  • Business Center
1.5 km from City Centre400 m from America's Center
From   US$ 209 /nightSelect
  • Indoor pool and 24-hour fitness center
  • Complimentary hot breakfast buffet offered
  • Pet-friendly with maximum weight limit
  • Indoor Pool
  • Kickback
  • Business Center
700 m from City Centre200 m from Union Station
From   US$ 141 /nightSelect
  • Complimentary evening snacks and drinks
  • Historic ambiance with modern amenities
  • Heated indoor pool and hot tub
  • Valet parking
  • Fitness center
  • Business center
700 m from City Centre400 m from City Museum
From   US$ 176 /nightSelect
  • Proximity to Gateway Arch and museums
  • Historic building charm with modern amenities
  • Pet-friendly with designated room options
  • Fitness Center
  • Bistro
  • On-site Parking
1.1 km from City Centre700 m from Union Station
From   US$ 118 /nightSelect
  • Direct views of Gateway Arch
  • Unique dining experience at Bistro
  • Wheelchair accessibility features
  • Rooftop Bar
  • In-house Dining
  • Business Center
1.6 km from City Centre300 m from Gateway Arch
From   US$ 235 /nightSelect
  • Baseball-themed decor enhances unique atmosphere
  • Rooftop bar offers stunning city views
  • In-house dining at Clark & Bourbon restaurant
  • Robie's Restaurant
  • Fitness Center
  • Meeting Space
1.0 km from City Centre400 m from America's Center
From   US$ 154 /nightSelect
  • Historic hotel with luxury suites
  • On-site dining with locally sourced cuisine
  • Pet-friendly with no additional fee
  • AC Lounge
  • Fitness Center
  • Meeting Space
5.6 km from City Centre1.8 km from Saint Louis Science Center
From   US$ 409 /nightSelect
  • Chic interior design with modern aesthetics
  • Exceptional staff service from dedicated team
  • Proximity to cultural attractions and dining
  • Heated Pool
  • On-site Dining
  • Fitness Center
6.8 km from City Centre1000 m from Saint Louis Science Center
From   US$ 175 /nightSelect
  • Unique heated pool with family amenities
  • Community-focused staff provide personalized service
  • Coupons for local attractions available
  • Fitness Center
  • Outdoor Fire Pit
  • Business Center
900 m from City Centre500 m from Union Station
From   US$ 139 /nightSelect
  • Stunning views of Gateway Arch and skyline
  • Outdoor seating area with fire pit
  • Variety of complimentary breakfast options
  • On-site Spa
  • Business Center
  • Italian Restaurant
800 m from City Centre200 m from Busch Stadium
From   US$ 129 /nightSelect
  • Loft-style guest rooms with modern decor
  • Italian restaurant with local craft beers
  • Accessible facilities for all guests
  • Fitness Center
  • Business Center
  • On-Site Dining
700 m from City Centre700 m from Enterprise Center
From   US$ 424 /nightSelect
  • European-inspired gelato bar experience
  • Modern lobby for guest interactions
  • Accessible facilities for all guests
  • On-site Bistro
  • Business Center
  • 24-hour Fitness
1.1 km from City Centre300 m from America's Center
From   US$ 169 /nightSelect
  • Direct access to convention center
  • Unique local art in guest rooms
  • Rooms accommodating up to 8 guests